- 1 How does folate affect B12?
- 2 Why is it important to avoid high doses of vitamin B12 and folate?
- 3 Why folic acid is contraindicated in pernicious anemia?
- 4 Why do B12 and folate deficiencies cause anemia?
- 5 What are the side effects of too much folate?
- 6 Is folate and vitamin B12 the same thing?
- 7 What symptom of vitamin B12 deficiency is masked by high folate intake?
- 8 Should I be worried if my B12 is high?
- 9 Can I take B12 twice a day?
- 10 Can you take folic acid and vitamin B12 together?
- 11 Does folic acid treat B12 deficiency?
- 12 Which is one of the first symptoms of folate deficiency?
- 13 How long does it take to correct folate deficiency?
- 14 How do you know if your B12 is low?
- 15 How long does it take to recover from B12 deficiency?
How does folate affect B12?
Folic acid works closely with vitamin B12 in making red blood cells and helps iron function properly in the body. Vitamin B9 works with vitamins B6 and B12 and other nutrients in controlling the blood levels of the amino acid homocysteine.
Why is it important to avoid high doses of vitamin B12 and folate?
There is concern that high intakes of folic acid from fortified food and dietary supplements might mask the macrocytic anemia of vitamin B12 deficiency, thereby eliminating an important diagnostic sign.
Why folic acid is contraindicated in pernicious anemia?
Folic acid should never be given alone in the treatment of Addisonian pernicious anaemia and other vitamin B12 deficiency states because it may precipitate the onset of subacute combined degeneration of the spinal cord.
Why do B12 and folate deficiencies cause anemia?
Vitamin B12 or B9 (commonly called folate) deficiency anaemia occurs when a lack of vitamin B12 or folate causes the body to produce abnormally large red blood cells that cannot function properly. Red blood cells carry oxygen around the body using a substance called haemoglobin.
What are the side effects of too much folate?
Although doses up to 5 mg daily have been safely used in some research, doses of folic acid greater than 1 mg daily might cause abdominal cramps, diarrhea, rash, sleep disorders, irritability, confusion, nausea, stomach upset, behavior changes, skin reactions, seizures, gas, excitability, and other side effects.
Is folate and vitamin B12 the same thing?
Vitamin B12, also called cobalamin, is found in foods from animals, such as red meat, fish, poultry, milk, yogurt, and eggs. Folate (Vitamin B9) refers to a natural occurring form of the vitamin, whereas folic acid refers to the supplement added to foods and drinks.
What symptom of vitamin B12 deficiency is masked by high folate intake?
The results of the first study suggest that during vitamin B12 deficiency, high serum folate levels exacerbate (rather than mask) anemia and also exacerbate cognitive symptoms.
Should I be worried if my B12 is high?
Though daily high doses of B12 are unlikely to cause harm in most people, extremely high doses should be avoided unless prescribed by a healthcare professional. If you think you may be deficient in B12, speak with your doctor, who can recommend an appropriate treatment based on your level of deficiency.
Can I take B12 twice a day?
Early research suggests that taking twice the recommended daily allowance of vitamin B12, with or without folic acid, does not reduce the risk of diarrhea in children.
Can you take folic acid and vitamin B12 together?
No interactions were found between folic acid and Vitamin B12. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Does folic acid treat B12 deficiency?
Before you start taking folic acid, your GP will check your vitamin B12 levels to make sure they’re normal. This is because folic acid treatment can sometimes improve your symptoms so much that it masks an underlying vitamin B12 deficiency.
Which is one of the first symptoms of folate deficiency?
Common symptoms of folate deficiency can include:
- Tiredness, fatigue and lethargy.
- Muscle weakness.
- Neurological signs, such as a feeling of pins and needles, tingling, or burning, or peripheral neuropathy, i.e. a numbness in the extremities.
How long does it take to correct folate deficiency?
The body has about 1,000-20,000 mcg of folate stores, and adults need about 400 mcg/d to replenish the daily losses. Folate deficiency may take 8-16 weeks to become evident.
How do you know if your B12 is low?
Symptoms of Vitamin B12 Deficiency
- Weakness, tiredness, or lightheadedness.
- Heart palpitations and shortness of breath.
- Pale skin.
- A smooth tongue.
- Constipation, diarrhea, loss of appetite, or gas.
- Nerve problems like numbness or tingling, muscle weakness, and problems walking.
- Vision loss.
How long does it take to recover from B12 deficiency?
Recovery from vitamin B12 deficiency takes time and you may not experience any improvement during the first few months of treatment. Improvement may be gradual and may continue for up to six to 12 months.