Question: Vitamin B12 What Levels Are Considered Too High?

Is B12 level of 2000 too high?

Though doses of up to 2,000 mcg of vitamin B12 are considered safe, it’s best to speak to a doctor to find out whether taking a supplement is necessary. Most people can fill their B12 needs through a healthy diet. Some, such as older adults or those with certain dietary restrictions, should supplement.

Is B12 level of 1500 too high?

There is no consensus on the definition of high or elevated B12. Previous studies have chosen a variety of levels to represent high or very high B12 (pmol/l) levels. Some examples include: 664.219; 5131; 700 (high) and 1500 (very high)11; and 601 (high) and 1000 (very high)10.

What happens if Vitamin B12 is high?

However, supplementing with excessively high levels of B12 has been linked to some negative side effects. Several studies have shown that megadoses of the vitamin can lead to outbreaks of acne and rosacea, a skin condition that causes redness and pus-filled bumps on the face.

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What is a good level of vitamin B12 in blood?

But a normal level of vitamin B12 in your bloodstream is generally between 190 and 950 picograms per milliliter (pg/mL). Between 200 to 300 pg/mL is considered borderline and your doctor may do more testing. Below 200 pg/mL is low and more testing is needed.

What does high B12 mean in blood test?

Elevated levels of serum cobalamin may be a sign of a serious, even life-threatening, disease. Hematologic disorders like chronic myelogeneous leukemia, promyelocytic leukemia, polycythemia vera and also the hypereosinophilic syndrome can result in elevated levels of cobalamin.

What causes high levels of B12 in the blood?

The most common cause of high B12 in the blood is due to recent ingestion or injection of supplemental vitamin B12. We don’t worry about overdosing on B12 supplements because excess can be excreted in your urine. It could also be possibly from your diet if high in animal products such as meat, eggs, and shellfish.

How do I lower my B12 levels?

You can change your diet to include vitamin B12-fortified grains, a supplement or B12 injections, or a high-dose oral vitamin B12 if you are deficient. Older adults who have a vitamin B12 deficiency will likely have to take a daily B12 supplement or a multivitamin that contains B12.

Can fatty liver cause high B12 levels?

The levels of vitamin B12 were correlated with the stage of NAFLD, lipid profile and liver parameters. Results: Vitamin B12 levels were significantly lower in patients with NAFLD. Vitamin B12 levels inversely correlated with cholesterol and triglyceride levels.

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How long does it take to get rid of excess B12?

If a person stops consuming the vitamin, the body’s stores of this vitamin usually take about 3 to 5 years to exhaust. People should not take high doses of vitamin B12 as a cure-all, but otherwise the vitamin does not appear to be toxic; consuming excess amounts of B12 is not recommended.

Can Vitamin B12 damage your liver?

Some studies have indicated that elevated serum levels of vitamin B12 might be a sign of a serious and life-threatening disease. Such falsely high valued of serum vitamin B12 levels are observed in myeloproliferative disease, acute hepatitis, severe alcoholic liver disease, and cirrhosis.

Is 500 a good B12 level?

The vitamin B12 standard reference range is 200–700 pg/ml whereas the proposed optimal range is 500–1300 pg/ml [10]. Higher vitamin B12 ranges have been associated with increased cognitive function, and reflexes, decreased brain atrophy, confusion, weakness and depression [10].

Does high B12 mean deficiency?

Deficiency should be confirmed by checking the level of a substance in the blood called methylmalonic acid. A high level indicates a true B12 deficiency. Causes of vitamin B12 deficiency include: Not enough vitamin B12 in diet (rare, except with a strict vegetarian diet)

What is normal level of vitamin B12 in elderly?

A serum vitamin B12 level between 200 pg/mL and 900 pg/mL is considered normal, but a threshold of 300 to 350 pg/mL is recognized as a marker for a desirable status in the elderly. The laboratory diagnosis is usually based on low serum vitamin B12 levels or elevated serum methylmalonic acid and homocysteine levels.

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