Question: ____________, Which Is Secreted By ___________ Cells, Is Necessary For Vitamin B12 Absorption.?

Which is secreted by cells is necessary for vitamin B12 absorption?

Intrinsic factor is a glycoprotein secreted by parietal cells and is necessary for the absorption of vitamin B12 in the terminal ileum.

What is required for vitamin B12 absorption in small intestine?

Vitamin B12 occurs in foods that come from animals. Normally, vitamin B12 is readily absorbed in the last part of the small intestine (ileum), which leads to the large intestine. However, to be absorbed, the vitamin must combine with intrinsic factor, a protein produced in the stomach.

Which substance necessary for vitamin B12 absorption is produced by the parietal cells in the stomach?

Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells (in humans) or chief cells (in rodents) of the stomach. It is necessary for the absorption of vitamin B12 later on in the distal ileum of the small intestine.

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Which of the following cells secrete HCL hydrochloric and intrinsic required for vitamin B12 absorption?

In a healthy person, intrinsic factor is produced by the parietal cells of the stomach, the cells that also secrete hydrochloric acid. Intrinsic factor forms a complex with dietary vitamin B12 in the stomach.

What is Pepsinogen secreted by?

Pepsin is a stomach enzyme that serves to digest proteins found in ingested food. Gastric chief cells secrete pepsin as an inactive zymogen called pepsinogen.

Can you absorb B12 without intrinsic factor?

A small amount of vitamin B12 is absorbed by passive diffusion without intrinsic factor.

Does B12 deficiency cause malabsorption?

enterocyte caused by severe vitamin B12deficiency, which is rapidly corrected by giving vitamin B12. Binding of intrinsic factor by intrinsic factor anti- bodies secreted into the gastric juice or bacterial overgrowth of the small bowel may contribute to the malabsorption in some patients.

What is the best way to absorb vitamin B12?

We already know from Harvard that B12 absorption can be increased by taking folate (another B vitamin, this one found in higher amounts in chickpeas, liver, pinto beans, lentils, spinach, asparagus, and avocado, among others).

Where is folic acid absorbed?

Folates are absorbed primarily in the duodenum and jejunum within the acid microenvironment at the cell surface.

Is required for absorption of vitamin B12 quizlet?

Adequate absorption of vitamin B12 requires adequate dietary intake, the presence of acid and pepsin in the stomach and proteases from the pancreas, functional intrinsic factor in gastric secretions, and an ileum with functioning receptors specific to vitamin B12.

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What causes lack of intrinsic factor?

The inability to make intrinsic factor may be caused by several things, such as: Chronic gastritis. Surgery to remove all or part of the stomach (gastrectomy) An autoimmune condition, where the body attacks its own tissues.

How is vitamin B12 absorbed into the body?

Normally, vitamin B12 is readily absorbed in the last part of the small intestine (ileum), which leads to the large intestine. However, to be absorbed, the vitamin must combine with intrinsic factor, a protein produced in the stomach.

What is an example of an intrinsic factor?

These factors include a person’s age, organ function (e.g., liver, kidney, cardiovascular), and co-morbid diseases. Finally, intrinsic factors also include characteristics that can be influenced by both genetics and a person’s physiology/pathology, such as height, body weight, and receptor sensitivity.

Which medicine is best for vitamin B12 deficiency?

Drugs used to treat Vitamin B12 Deficiency

Drug name Rating Rx/OTC
View information about Vitamin B12 Vitamin B12 6.7 Rx/OTC
Generic name: cyanocobalamin systemic Drug class: vitamins For consumers: dosage, interactions, side effects
View information about cyanocobalamin cyanocobalamin 6.8 Rx/OTC

What is the function of intrinsic factor in vitamin B12 absorption?

Intrinsic factor is a protein that helps your intestines absorb vitamin B12. It is made by cells in the stomach lining.

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